About Canesten®

More than 35 Years

More than 35 years of global clinical experience have made Canesten® what it is today: an effective and generally well tolerated drug product for fungal infections.

Modern antifungal research got underway after World War II and then intensified in the 1950s and 1960s as a result of the massive increase in fungal infections. Bayer was amongst those who responded to this challenge and established a research laboratory for medicinal mycology in 1963. The breakthrough to active substances with a broad spectrum of antifungal action was achieved with the discovery of the azole derivatives by the Bayer researcher Prof. Karl Heinz Büchel who succeeded in synthesising the first azole derivative, clotrimazole, in the late 1960s.

Clotrimazole was registered in Germany for the first time in 1973 and launched on the market under the brand name Canesten®. The first presentations for treatment of fungal skin infections were the Cream and Solution (Pumpspray), while Canesten® Vaginal Tablets were developed for treatment of gynaecological fungal vaginal infections. In the late 1970s, the range was extended by the addition of the Canesten® Vaginal Cream.

Thanks to their efficacy and tolerability, the dermatological Canesten® products were registered for self-medication in 1977. The gynaecological presentations for 1-day and 3-day therapy were initially granted Over-the-Counter status (available without prescription) in Canada in 1994. Canesten® is now available without prescription in most countries.

Think Canesten First

Canesten® is a global market leader for treatment of dermatological and gynaecological fungal infections. Canesten® contains the original active ingredient clotrimazole developed by Bayer. Clotrimazole was introduced into the market in 1973 world-wide.


The variety of the product range allows fast, reliable and convenient use against fungal diseases. Today, Canesten® is available in more than 80 countries. Bayer researchers continuously develop innovative and effective remedies for new areas of application for all types of fungal diseases.